![D-dopachrome Tautomerase (D-dt): Functional Homologue or Cross-regulator of Macrophage Migration Inhibitory Factor (Mif)? - Wibke Karin Schulte - Bøker - Südwestdeutscher Verlag für Hochschulsch - 9783838131610 - 23. februar 2012](https://imusic.b-cdn.net/images/item/original/610/9783838131610.jpg?wibke-karin-schulte-2012-d-dopachrome-tautomerase-d-dt-functional-homologue-or-cross-regulator-of-macrophage-migration-inhibitory-factor-mif-pocketbok&class=scaled&v=1408617389)
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D-dopachrome Tautomerase (D-dt): Functional Homologue or Cross-regulator of Macrophage Migration Inhibitory Factor (Mif)?
Wibke Karin Schulte
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D-dopachrome Tautomerase (D-dt): Functional Homologue or Cross-regulator of Macrophage Migration Inhibitory Factor (Mif)?
Wibke Karin Schulte
Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine and a pivotal regulator of the immune response implicated in the pathogenesis of various acute and chronic inflammatory diseases. In 1993, D-dopachrome tautomerase (D-DT) was discovered during an investigation of melanogenesis. The tertiary structure of D-DT is remarkably similar to MIF, identifying D-DT as the only known eukaryotic MIF homologue discovered to date. Despite D-DT?s intriguing similarities to the very well studied MIF, there have been very few reports on the biological functions and mechanisms of action of D-DT. This dissertation aimed at the functional characterization of D-DT in biological and pathophysiologic conditions.
Media | Bøker Pocketbok (Bok med mykt omslag og limt rygg) |
Utgitt | 23. februar 2012 |
ISBN13 | 9783838131610 |
Utgivere | Südwestdeutscher Verlag für Hochschulsch |
Antall sider | 100 |
Mål | 150 × 6 × 226 mm · 158 g |
Språk | Engelsk |
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